Sodium and Potassium enzymatic Testkit

The new Centronic enzymatic reagents for the determination of

Sodium and Potassium can be measured on all common analysers and

are a reliable alternative to often used ISE.

Basics:

Sodium and Potassium play essential roles in every electrolyte metabolism.
Both have to be measured to identify an electrolyte imbalance.
Therefore the control of these electrolytes within a disease diagnosis is very important.

Indications:

Potassium:

Potassium is the most frequent intracelluar cation. The internal Potassium-Homeostasis is regulated by a Sodium/Potassium pump between the extracellular- and the intracellular area. Significant dysfunctions can appear already at a loss of 1% of the total potassium.

Normal range: 3.3-5.4 mmol/l

Possible indications:

- Too low:
-- Dysfunction in circulation through Alkalosis, Insulin increases, increses in Catecholamines
-- Decrease of the total potassium in the organism through renal loss, gastrointestinal loss (Diarrhea, vomiting etc.)

- Too high:
-- Dysfunction in circulation through Azidosis, Diabetes mellitus etc.
-- Increase of the total potassium in the organism through renal failure, morbus Addison, special diuretica, decomposition of tissue (tumors, lymphomes, cytostatics, hemolysis etc.)
-- high takings of potassium
-- artificial increase through whole blood sample storage of longer than 2-4 hours, longer congestion during blood sampling and hemolysis in the sample tube

Sodium:
- Too high:
-- Dehydratation through
--- reduced hydration
--- increased ullage (diarrhea, fever, strong perspiration, polyuria)
--- renal diabetes inspidus (nephrocalcinosis etc.)
--- central diabetes inspidus (craniocerebral injury)
-- Hyperhydratation through
--- increased intake of NaCl
--- increased back resorption of sodium (limited renal function)

- Too low:
-- Hyperhydratation (renal failure, cardiac infarction etc.)
-- Euvolemia (syndrom of inadequate ADH secretion at brain tumor, tuberculosis etc.)
-- Dehydratation (vomiting, diarrhea, morbus addison etc.)

Normal range: 135-145 mmol/l (adults), 133-143 mmol/l (children)

Test Specifications: