Sodium and Potassium enzymatic Testkit

The new Centronic enzymatic reagents for the determination of

Sodium and Potassium can be measured on all common analysers and

are a reliable alternative to often used ISE.



Sodium and Potassium play essential roles in every electrolyte metabolism.
Both have to be measured to identify an electrolyte imbalance.
Therefore the control of these electrolytes within a disease diagnosis is very important.



Potassium is the most frequent intracelluar cation. The internal Potassium-Homeostasis is regulated by a Sodium/Potassium pump between the extracellular- and the intracellular area. Significant dysfunctions can appear already at a loss of 1% of the total potassium.

Normal range: 3.3-5.4 mmol/l

Possible indications:

- Too low:
-- Dysfunction in circulation through Alkalosis, Insulin increases, increses in Catecholamines
-- Decrease of the total potassium in the organism through renal loss, gastrointestinal loss (Diarrhea, vomiting etc.)

- Too high:
-- Dysfunction in circulation through Azidosis, Diabetes mellitus etc.
-- Increase of the total potassium in the organism through renal failure, morbus Addison, special diuretica, decomposition of tissue (tumors, lymphomes, cytostatics, hemolysis etc.)
-- high takings of potassium
-- artificial increase through whole blood sample storage of longer than 2-4 hours, longer congestion during blood sampling and hemolysis in the sample tube

- Too high:
-- Dehydratation through
--- reduced hydration
--- increased ullage (diarrhea, fever, strong perspiration, polyuria)
--- renal diabetes inspidus (nephrocalcinosis etc.)
--- central diabetes inspidus (craniocerebral injury)
-- Hyperhydratation through
--- increased intake of NaCl
--- increased back resorption of sodium (limited renal function)

- Too low:
-- Hyperhydratation (renal failure, cardiac infarction etc.)
-- Euvolemia (syndrom of inadequate ADH secretion at brain tumor, tuberculosis etc.)
-- Dehydratation (vomiting, diarrhea, morbus addison etc.)

Normal range: 135-145 mmol/l (adults), 133-143 mmol/l (children)

Test Specifications: